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efavirenz manufacturer Chandraprabhu Pharma

efavirenz manufacturer


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Product Name :
EFAVIRENZ
Chemical Formula :
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
CAS No :
154598-52-4
Molecular Formula :
C14H9ClF3NO2
Molecular Weight :
315.675
efavirenz
Description :
Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly activeantiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to reduce the risk of HIV infection in people exposed to a significant risk (e.g. needlestick injuries, certain types of unprotected sex etc.). Efavirenz falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.

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