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levonorgestrel manufacturer Chandraprabhu Pharma

levonorgestrel manufacturer


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Product Name :
LEVONORGESTREL
Chemical Formula :
13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one
CAS No :
797-63-7
Molecular Formula :
C21H28O2
Molecular Weight :
312.446
levonorgestrel
Description :
Levonorgestrelis a second generation syntheticprogestogenused as an active ingredient in somehormonal contraceptives, includingcombined oral contraceptive pills,progestogen only pills,emergency contraceptive pills,intrauterine systems, and contraceptive implants. Levonorgestrel (levo=left) is one form of a hormone that exists in two mirror image left and right forms. Chemically, it is a hormonally active levorotatory enantiomer of the racemic mixture norgestrel. It is a gonane progestin derived from 19-nortestosterone. If taken together with drugs that induce the CYP3A4 cytochrome liver enzyme, the levonorgestrel will be metabolized faster and have lower efficacy, and a larger dose will be needed. At low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250 g, and triphasic doses of 50 g/75 g/125 g. Levonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel-only method. The primary mechanism of action of levonorgestrel as a progestogen-only emergency contraceptive pill is to prevent fertilization by inhibition of ovulation.

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