Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /home/content/93/7713193/html/chandraprabhu/includes/dbconfig.php on line 20
pemetrexed manufacturer Chandraprabhu Pharma

pemetrexed manufacturer


Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /home/content/93/7713193/html/chandraprabhu/includes/dbconfig.php on line 20
Product Name :
PEMETREXED
Chemical Formula :
(2S)-2-{[4-[2-(2-amino-4-oxo-1,7-dihydro pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino} pentanedioic acid
CAS No :
137281-23-3
Molecular Formula :
C20H21N5O6 
Molecular Weight :
427.411
pemetrexed
Description :
Pemetrexed is a chemotherapy drug. Its indications are the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyl transferase(GARFT). By inhibiting the formation of precursor purine and pyrimidine nucleotides, pemetrexed prevents the formation of DNA and RNA, which are required for the growth and survival of both normal cells and cancer cells.

Submit Enquiry