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pioglitazone manufacturer Chandraprabhu Pharma

pioglitazone manufacturer


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Product Name :
PIOGLITAZONE
Chemical Formula :
(RS)-5-(4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4-dione
CAS No :
111025-46-8
Molecular Formula :
C19H20N2O3S 
Molecular Weight :
356.44
pioglitazone
Description :
Pioglitazone is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. Pioglitazone selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-?) and to a lesser extent PPAR-?. It modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the muscle, adipose tissue, and the liver. As a result, pioglitazone reduces insulin resistance in the liver and peripheral tissues; increases the expense of insulin-dependent glucose; decreases withdrawal of glucose from the liver; reduces quantity of glucose, insulin and glycated hemoglobin in the bloodstream. Pioglitazone and other active TZDs binds to the outer mitochondrial membrane protein mitoNEET with affinity comparable to that of pioglitazone for PPAR?

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