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terbinafine manufacturer Chandraprabhu Pharma

terbinafine manufacturer


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Product Name :
TERBINAFINE
Chemical Formula :
[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine
CAS No :
91161-71-6
Molecular Formula :
C21H25N 
Molecular Weight :
291.43
terbinafine
Description :
Terbinafine hydrochloride is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, fatty tissues, bacterias of the duodenum and viral infections of the stomach. Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.

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